Supervillin

Interactor Gene Name:
SVIL
Interactor protein name:
Supervillin
Uniprot ID:
O95425
Identifed in (species):
Human
Cell Type/ Tissue:
HEK
Receptor (species):
Rat
Interactor (species):
Human
Experimental System:
Stable transgenic expression
Detection Method:
Co-IP / WB
Published (year):
2001
Publication (PubMed):
Kim M (2001)
Protein Structure of Interactor:
RSCB PDB
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM; GAD

SupervillinĀ belongs to the gelsolin-related actin binding protein family. It possesses F-actin binding domains, myosin II-binding domain and intrinsic actin-bundling activity.

SupervillinĀ modulates focal adhesions, cell motility, cell spreading, membrane trafficking and membrane-based signalling.