Peripheral plasma membrane protein CASK

Interactor Gene Name:
CASK
Interactor protein name:
Peripheral plasma membrane protein CASK
Uniprot ID:
O14936
Identifed in (species):
Human
Cell Type/ Tissue:
Liver cDNA library
Receptor (species):
Human
Interactor (species):
Human
Detection Method:
Yeast two-hybrid
Published (year):
2011
Publication (PubMed):
Wang J (2011)
Protein Structure of Interactor:
RSCB PDB
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM; GAD

CASK is a calcium/calmodulin-dependent serine protein kinase and a member of MAGUK (membrane-associated guanylate kinase) protein family. It a scaffolding protein located at synapses in the brain.

CASK regulates targeting, trafficking and signalling of ion channels. It also plays a role in neuronal development and regulation of gene expression.