Nucleoprotein TPR

Interactor Gene Name:
TPR
Interactor protein name:
Nucleoprotein TPR
Uniprot ID:
P12270
Identifed in (species):
Human
Cell Type/ Tissue:
HEK 293
Receptor (species):
Human
Interactor (species):
Human
Experimental System:
Transgenic expression
Detection Method:
Co-IP / Mass Spec
Published (year):
2009
Publication (PubMed):
Gu BJ (2009)
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM

TPR is a coiled-coil protein, component of nuclear pore complex. It is involved in nuclear export of mRNAs and some proteins.

Several chromosome translocations resulting in fusion of TPR with protein kinase domains of proto-oncogenes have been reported in human tumours.