Nitric oxide synthase, brain

Interactor Gene Name:
NOS1
Interactor protein name:
Nitric oxide synthase, brain
Uniprot ID:
Q9Z0J4
Identifed in (species):
Mouse
Cell Type/ Tissue:
Prefrontal cortex, striatum and hippocampus
Receptor (species):
Mouse
Interactor (species):
Mouse
Experimental System:
Endogenous expression
Detection Method:
Co-IP / WB
Published (year):
2013
Publication (PubMed):
Pereira VS (2013)
Protein Structure of Interactor:
RSCB PDB
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM; GAD

NOS1 generates nitric oxide; its activity is regulated by calcium and calmodulin. It is constitutively expressed in the central and peripheral nervous system.

NOS1 modulates physiological functions such as learning, memory and neurogenesis. It is also involved in regulation of blood pressure.