Neutrophil defensin 1

Interactor Gene Name:
DEFA1
Interactor protein name:
Neutrophil defensin 1
Uniprot ID:
P59665
Identifed in (species):
Human
Cell Type/ Tissue:
HEK 293
Receptor (species):
Human
Interactor (species):
Human
Experimental System:
transgenic expression
Detection Method:
GST pull-down assay, confocal microscopy
Published (year):
2013
Publication (PubMed):
Chen Q (2013)
Protein Structure of Interactor:
RSCB PDB
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM; GAD

Neutrophil defensin 1 belongs to α-defensins, which are small cationic peptides with microbicidal and cytotoxic properties. It is constitutively expressed in neutrophils and is involved in host defence.

Neutrophil defensin 1 is ADP-ribosylated by human ADP-ribosyltranferase 1 (ART1).