MAGUK p55 subfamily member 3

Interactor Gene Name:
MPP3
Interactor protein name:
MAGUK p55 subfamily member 3
Uniprot ID:
Q13368
Identifed in (species):
Human
Cell Type/ Tissue:
HEK 293
Receptor (species):
Rat
Interactor (species):
Human
Experimental System:
Stable transgenic expression
Detection Method:
Co-IP / Mass Spec
Published (year):
2001
Publication (PubMed):
Kim M (2001)
Protein Structure of Interactor:
RSCB PDB
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM

MPP3 belongs to the family of membrane-associated guanylate kinase homologs. It contains a Src homology 3 (SH3) domain. It is a scaffolding protein, interacts with cytoskeleton and several other proteins.

MPP3 is involved in regulation of cell proliferation, signalling pathways and intracellular junctions. It plays a role in the development of the cortex.