Epithelial membrane protein 2

Interactor Gene Name:
EMP2
Interactor protein name:
Epithelial membrane protein 2
Uniprot ID:
P54849
Identifed in (species):
Human
Cell Type/ Tissue:
HEK, HEK library
Receptor (species):
Rat
Interactor (species):
Human
Experimental System:
transgenic co-expression
Detection Method:
yeast two-hybrid asay, GST pull-down
Interaction Domain (P2X7):
C-terminus 356-595
Experimental Confirmation:
Co-IP / WB; co-purification His-tag
Published (year):
2002
Publication (PubMed):
Wilson HL (2002)
Sequence:
NCBI Gene
Expression Profile:
EMBL-EBI Expression Atlas
Disease Pathways:
OMIM; GAD

EMP-2 belongs to the peripheral myelin protein 22 (PMP22) family (together with EMP-1 and EMP-3), which are tetraspan transmembrane proteins.

It plays an important role in blastocyst implantation with the uterine endometrium. It plays a role in female reproductive cancers.